Cosmetic Raw Materials, Anti-Wrinkle and Anti-Aging Palmitoyl Pentapeptide-4

• CAS No.: 214047-00-4
• Formula: C39h75n7o10
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Colour: White
• Transport Package: Drum
• Specification: 98%
• Origin: China

Product Description

 

Product Description

Palmitoyl pentapeptide is a widely used penta-peptide, can promote the skin synthesis of more collagen and hyaluronic acid and other substances, has the effect of reducing wrinkles, increasing skin elasticity and reversing aging.

Palmitoyl pentapeptide is a Pal - KTTKS containing five peptides, the peptide can through interaction with special cells receiver to regulate cell activity, the activation and extracellular matrix updating the activity of genes related to cell proliferation, prompting moreskin synthesis of collagen and hyaluronic acid and other substances, reduce wrinkles, increase skin elasticity effect, can effectively reverse aging.


 

Palmitoyl Pentapeptide-4 (Pal-Lys-Thr-Thr-Lys-Ser = Pal-KTTKS) contains 5 amino acids linked to a 16-carbon aliphatic chain for improving the penetration of the molecule through the lipid structures of the skin. messenger peptides capable of regulating cell activities by interacting with their specific receptors. They activate certain genes involved in the process of extracellular matrix renewal and cell proliferation. By activating the neosynthesis of extracellular matrix macromolecules, palmitoyl pentapeptide-4 provides an anti-wrinkle effect.


 

Function and Application

Palmitoyl pentapeptide is a small molecule chemical with a chemical molecular structure of C39H75N7O10, which has whitening and anti-wrinkle effects. It is often used in beauty products and contains rich nutrients.
(1) Fight against wrinkles and shape firm contours;
(2) Smoothen fine lines and reduce wrinkles;
(3) Inhibit nerve transmission and eliminate expression lines;
(4) Improve skin elasticity, skin elasticity and smoothness.

Product Introduction:
Palmitoyl Pentapeptide-4 (Pal-Lys-Thr-Thr-Lys-Ser = Pal-KTTKS) contains 5 amino acids linked to a 16-carbon aliphatic chain for improving the penetration of the molecule through the lipid structures of the skin. It is a matricide. Matrikines are messenger peptides capable of regulating cell activities by interacting with their specific receptors. They activate certain genes involved in the process of extracellular matrix renewal and cell proliferation. By activating the neosynthesis of extracellular matrix macromolecules, palmitoyl pentapeptide-4 provides an anti-wrinkle effect. [medical citation needed] Studies (in vitro and in vivo) demonstrating the anti-wrinkle efficacy of this peptide have been conducted and published by Sederma and by independent organisations.

Application:
skin care-aging, repair.

Usage:
Palmitoyl Pentapeptide-4 helps stimulate collagen synthesis and elastin. The action is very similar to retinol without the irritation.

What are Peptides for Skin Care?
Science has proven that peptides can help manage wrinkles in your skin and reverse the signs of aging. Human skin is comprised mostly of collagen. Collagen is a protein comprised of long segments of amino acids arranged like a chain. Collagen provides a foundation and thickness for skin. Women under 30 have ample collagen, which results in smooth, tight skin. The rest of us have less collagen - skin tends to be thinner, revealing more wrinkles. When collagen breaks down, short segments of amino acids are formed. These are the tiny proteins and active molecules known as peptides. Peptides in skin care can provide significant anti-aging benefits.



 

Item of Analysis	Specification	Results	Test Methods
Assay(on the anhydrous basis )	98%~101%	99.20%	HPLC
Appearance	White powder	Conform	Visual
Identification
A: IR	Corresponds qualitatively to the reference	Complies	USP41-NF36
B: Color Reaction	A blue color appears	Positive	USP41-NF36
Water(KF)	≤0.2%	0.03%	USP41-NF36
Residue on ignition	≤0.1%	0.02%	USP41-NF36
Mesh size	Not less than 90% pass 80 mesh	Complies	80 mesh screen
Residual Solvents	Ethanol ≤1000ppm	18ppm	USP41-NF36
Heavy metals	Inorganic arsenic ≤3μg/g	0.06μg/g	USP41-NF36
	Total Hg ≤3μg/g	<0.01μg/g	USP41-NF36
	Lead ≤1μg/g	0.09μg/g	USP41-NF36
Chromatographic purity	Test 1: Coenzyme Q7,Q8,Q9,Q11 and related impurities:≤1.0% Test 2: 2Z isomer and related impurities:≤1.0% Test 1 & Test 2:  ≤1.5% Test 3: The single related impurities≤0.3%	0.37% 0.05% 0.42% 0.25%	USP41-NF36
Total Plate Count	≤1000cfu/g	<10 cfu/g	USP41-NF36
Yeast & Mold	≤100cfu/g	<15 cfu/g	USP41-NF36
E. Coli.	Negative	Negative	USP41-NF36
Salmonelle	Negative	Negative	USP41-NF36
S.aureus	Negative	Negative	USP41-NF36