Amygdalin, also known as laevomandelonitrile or laetrile, is isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds. Since the early 1950s, a modified form of amygdalin has been promoted under the names laetrile and "Vitamin B17" as a cancer cure.
In reality, neither amygdalin nor any derivative such as laetrile is in any sense a vitamin. Laetrile is
the purified form of the compound amygdalin, which is found naturally in fruits and vegetables, particularly in the apricot pits and bitter almonds. Amygdalin was first isolated in 1830 and was used as an anticancer agent in Russia as early as It is believed that laetrile relieves the pain of cancer. One theory is that cancer cells contain large quantities of the enzyme beta-glucosidase.This enzyme breaks the amygdalin down and releases cyanide, a toxic chemical that then kills cancer cells.
Test |
Specification |
Results |
|
Cas No. |
29883-15-6 |
Conforms |
|
Molecular formula |
C20H27NO11 |
Conforms |
|
Molecular weight |
457.42800 |
Conforms |
|
Melting point |
223-226 °C(lit.) |
Conforms |
|
Appearance (visual test) |
White crystalline powder |
Conforms |
|
Assay |
≥99% |
99.6% |
|
Solubility-Visual tests |
|
|
|
1)in water |
Easily soluble in water, methanl, |
Conforms |
|
2) in Methanl and ethanol |
ethanol |
|
|
Residual Solvents-using Gas Chromatography |
|
|
|
a)Methaol |
≤3000ppm |
36ppm |
|
b) Ethanol; |
≤1000ppm |
15ppm |
|
c) Aceton; |
≤1000ppm |
10ppm |
|
d) Acetonitril |
≤500ppm |
0.5ppm |
|
Residue on Ignition |
≤0.1% |
0.01% |
|
Functions of Vitamin B17
1. Anti-tumor effect.
2. Lower blood sugar, hypolipidemic.
3. Anti-inflammatory and analgesic effects.
4. Inhibit the respiratory center, cough, and asthma.
5. Elimination of pigmentation, freckles, dark spots, so as to achieve the effect of beauty.
6. Has an effect on cough, asthma, chest full of phlegm, blood-Chun, dry, dry bowel constipation.
Application of Vitamin B17
1. Vitamin B17 can also be used in the pharmaceutical field.
2. It significantly reduced the plaque index and bacterial count.
3. It reduced oxidative stress and lowers the blood sugar level in the body.
4. It immobilizes and kills 100% human spermatozoa at high concentrations.
5. It lowers the lipid levels especially cholesterol and LDL-cholesterol in the body.
6. When in the cosmetic field, Amygdalin is a kind of treatment for anti-skin cancer.
7. It interferes with the life cycle of lice, inhibiting their ability to feed and preventing eggs from hatching.
8. It enhances lipid peroxidation in the liver and blood of tumor-bearing models and accompanied by significant decreases in the activities of GSH-dependent antioxidant.
9. When in health food field, Bitter Apricot kernel extract is widely used in food additives industry, which can be added into the dairy, beverage health care products, pastries, cold drinks, jelly, bread, milk and so on.