Epimedium Extract
Product Name: Epimedium Extract
Source: Epimedium Brevicornum L
Extraction Part: Whole Plant
Specification: 10:1, 20:1 5%-98% Epimedium Total Glycosides 5%-30% Epimedium Monoglycosides
Appearance: Light Yellow Powder
Description
Epimedium brevicornu Maxim. is a perennial herb with a plant height of 20-60 cm. The rhizome is thick and short, dark brown, and the leaves are basal and stem-borne. They are long-stalked, and the leaflets are papery or thickly papery. The leaf margins have thorns. The flowers are white or light yellow. The flowering period is May-June, and the fruiting period is June-August.
Epimedium grows under the forest, in the bushes beside the ditch, or in the shade and wet places on the hillside, at an altitude of 650-3500 meters. It is cultivated in Shaanxi, Gansu, Shanxi, Henan, Qinghai, Hubei, Sichuan and other regions in China.
The whole herb of Epimedium is used for medicinal purposes. It is mainly used to treat impotence and premature ejaculation, back pain and leg pain, numbness of the limbs, hemiplegia, neurasthenia, forgetfulness, tinnitus, dizziness and other symptoms. Modern research shows that Epimedium contains icariin, volatile oil, wax alcohol, phytosterols, tannins, vitamin E and other ingredients. It can stimulate sexual function and promote semen secretion in animals. It also has antihypertensive (causing peripheral vasodilation), hypoglycemic, diuretic, antitussive and expectorant effects, as well as vitamin E-like effects. Pharmacological experimental studies have shown that epimedium can increase cardiovascular blood flow, promote hematopoietic function, immune function and bone metabolism, and has anti-aging and anti-tumor effects.
Epimedium extract
Application
1. Medicine;
2. Health products.
3. Functional beverages
Description
Epimedium, also known as barrenwort, bishop's hat, fairy wings, horny goat wed, or yin yang huo (Chinese: ), is a genus of flowering plants in the family Berberidaceae. The majority of the species are endemic to China, with smaller numbers elsewhere in Asia, and a few in the Mediterranean region.
Epimedium species are deciduous or evergreen hardy perennials. The majority have four-parted "spider-like" flowers in spring.
The species used as a dietary supplement is Epimedium grandiflorum. It contains icariin, which is a weak PDE5 inhibitor in vitro.
Main Function
1. Improve sexual functions of male such as cure impotence, prospermia,barrenness, frigidity etc.
2 . Cure menopause high blood pressure
3. Strengthen internal secretion, anti-aging
4. Anti-cancer
Application Filed
1.In pharmaceutical field
2.In health product field
| Icariin Chemical Properties |
| Melting point |
223-225 ºC |
| alpha |
D15 -87.09° (in pyridine) |
| Boiling point |
948.5±65.0 °C(Predicted) |
| density |
1.55 |
| RTECS |
DJ2980500 |
| storage temp. |
room temp |
| solubility |
DMSO: soluble50mg/mL, clear, colorless to dark yellow |
| form |
Powder |
| pka |
5.90±0.40(Predicted) |
| color |
light yellow to yellow |
| λmax |
350nm(MeOH)(lit.) |
| Merck |
14,3617 |
| InChIKey |
TZJALUIVHRYQQB-XLRXWWTNSA-N |
| Safety Statements |
24/25 |
| WGK Germany |
3 |
| HS Code |
29389090 |
| |
| Icariin Usage And Synthesis |
| Description |
Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases. |
| References |
[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C "Application of icariin in preparation of medicine for preventing and treating sexual dysfunction"
[3] Patent CN 104739851 A "New application of icariin, or icariin derivatives or icariin salt" |
| Chemical Properties |
Light yellow to yellow solid |
| Uses |
hepatoprotective |
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